Veterinary Speciality: Oncology
The purpose of the current pilot study is to evaluate whether the combination of SQAP and radiation can improve the response to therapy in dogs with soft tissue sarcomas (a malignant tumor that arises from the soft tissues such as muscle, etc.). These tumors are often resistant to both radiation therapy and chemotherapy and the hope is that combining radiation and SQAP will improve disease control beyond the typical 6 months that is achieved by radiation when given alone.
The study will cover all aspects of the study including baseline bloodwork, CT planning for radiation, delivery of radiation, administration of SQAP and follow up visits/bloodwork. The study will cover any complications associated with the SQAP should they occur. The study will NOT cover the costs of medical or surgical conditions unrelated to the SQAP administration such as ear infection, bladder infection, etc.
The potential benefit to your dog is that the combination of SQAP and local radiation treatment will be more effective than radiation treatment alone by helping to shrink the tumor and/or keeping it from growing for a long period of time.
Your dog will undergo a baseline physical exam and bloodwork along with a CT scan of the mass (plus chest/lungs if needed to check for evidence of tumor spread). Your dog will then return for radiation therapy to the tumor which is given once per week over 4 weeks (total of 4 treatments). Approximately 60 minutes before the radiation is given, the SQAP will be administered through an IV catheter slowly over 20 minutes. We will be monitoring your dog closely with bloodwork and physical exam during the treatment part of the study over the first 4 weeks. Your dog will return 2 weeks after finishing the radiation, then 2 weeks after that, and then every 4 weeks up until 6 months post enrollment.
For questions regarding the clinical trial please email the clinical trials technician, Diane Welsh at: email@example.com
If you believe that your pet may be eligible for this study, please complete our prescreening questionnaire for owners.