Chronic kidney disease (CKD) is a major cause of morbidity in cats, especially as they age. The rate of progression in cats varies from months to years but can be managed through medical intervention and nutrition. Nutrition is arguably the most important aspect of CKD management. By manipulating the composition of a patient’s diet, we can slow the progression of disease, minimize uremic symptoms, and improve quality of life. The goal of this clinical trial is to investigate the effects of differing protein concentrations on muscle mass, as well as different phosphorus concentrations on progression of CKD.
Cats diagnosed with CKD IRIS (International Renal Interest Society) stages 1, 2 or 3 are eligible to participate.
Exclusion criteria include other uncontrolled systemic illnesses, complications of CKD such as kidney infection or ureteral obstruction, decompensation of CKD requiring hospitalization and intravenous fluid therapy.
Your cat will receive free cat food (dry and/or canned) and standard of care monitoring of CKD for up to 2 years as well as management of their disease by a board certified internal medicine specialist.
Sample or Data Requirements
After screening and enrollment, your cat will be randomized to receive a study diet, all of which would potentially be appropriate for this stage of your cat’s disease. You will be asked to transition your cat completely to that new diet over a period up to 6 weeks. You will be asked to bring your cat back for evaluation 1 month after enrollment and then every 3 months thereafter for up to 1-2 years, or until your cat progresses to the next stage of CKD. You will be asked to bring a fresh fecal sample with you to each visit and labwork and imaging will be performed at each visit.
For questions regarding the clinical trial please email the clinical trials technician, Diane Welsh at: firstname.lastname@example.org
Is Your Pet Eligible?
If you believe that your pet may be eligible for this study, please complete our prescreening questionnaire for owners.
If you believe you have a patient who is eligible for this clinical trial study or you would like additional information from the Clinical Trials Office at the Cummings Veterinary Medical Center, complete a referring physician questionnaire.