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Impact of diet in cats with kidney disease

Impact of Staged Dietary Approach on Quality and Quantity of Life in Cats with Chronic Kidney Disease

Sponsor: Purina

Status: Suspended

Species: Cat

Veterinary Speciality: Internal Medicine, Nutrition


Chronic kidney disease (CKD) is a major cause of morbidity in cats, especially as they age. The rate of progression in cats varies from months to years but can be managed through medical intervention and nutrition. Nutrition is arguably the most important aspect of CKD management. By manipulating the composition of a patient’s diet, we can slow the progression of disease, minimize uremic symptoms, and improve quality of life. The goal of this clinical trial is to investigate the effects of differing protein concentrations on muscle mass, as well as different phosphorus concentrations on progression of CKD.


Inclusion Criteria

Cats diagnosed with CKD IRIS (International Renal Interest Society) stages 1, 2 or 3 are eligible to participate.

Exclusion Criteria

Exclusion criteria include other uncontrolled systemic illnesses, complications of CKD such as kidney infection or ureteral obstruction, decompensation of CKD requiring hospitalization and intravenous fluid therapy.

Client Benefits

Your cat will receive free cat food (dry and/or canned) and standard of care monitoring of CKD for up to 2 years as well as management of their disease by a board certified internal medicine specialist.

Sample or Data Requirements

After screening and enrollment, your cat will be randomized to receive a study diet, all of which would potentially be appropriate for this stage of your cat’s disease. You will be asked to transition your cat completely to that new diet over a period up to 6 weeks. You will be asked to bring your cat back for evaluation 1 month after enrollment and then every 3 months thereafter for up to 1-2 years, or until your cat progresses to the next stage of CKD. You will be asked to bring a fresh fecal sample with you to each visit and labwork and imaging will be performed at each visit.

Contact Info

For questions regarding the clinical trial please email the clinical trials technician, Diane Welsh at:

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