Diarrhea or enterocolitis can be a potentially serious or fatal disease in horses. Early treatment and differentiation between horses with self-limiting versus life-threatening diarrhea is therefore critical in the early phase of the disease. Delayed treatment can result in multiple serious complications, severe body-wide illness and potentially death, while excessive, prophylactic treatment measures are expensive. Thus, the goal of this study is to determine if biochemical markers or clotting times of blood (biomarkers) can distinguish between horses that will recover from enterocolitis with minimal intervention and horses with more severe illness that require aggressive medical therapy, early in the disease course.
Rapid point-of-care testing for the presence of biomarkers in the blood will provide indication for more aggressive management of horses at risk for life-threatening complications from enterocolitis while reducing cost of treatment for those horses with predicted self-limiting diarrhea. This will help reduce the complications that can arise from delayed treatment, allow for early intervention when necessary, and improve outcomes in horses suffering from enterocolitis.
Horses >20 years of age that develop diarrhea in the hospital
Surgery within 7 days prior to onset of diarrhea.
The study will cover the costs of the blood tests to measure circulating inflammatory mediators. The other costs for the care of your horse are the same as you would experience normally. You understand that your animal’s participation in this study will not in any way affect his/her outcome.
For questions regarding the clinical trial please email the clinical trials technician, Diane Welsh at: email@example.com
Is Your Pet Eligible?
If you believe that your pet may be eligible for this study, please complete our prescreening questionnaire for owners.
If you believe you have a patient who is eligible for this clinical trial study or you would like additional information from the Clinical Trials Office at the Cummings Veterinary Medical Center, complete a referring physician questionnaire.